Earlier this week, CCAMF (Centru Avansat de Cercetări Medicale și Farmaceutice), at UMFST, hosted a clinical study coordinated by the Department of Cosmetology (Pharmacy), staff from CCAMF and Cambridge Medical Technologies (CMT).
Dr Nicoleta Todoran and Dr Magdalena Birsan (University of Iasi), worked alongside Jack Jachmann (CEO of CMT) -who flew in from Rockville, Maryland in the US- to test a novel nanotechnological device for painless, non-invasive induction of skin permeability. Jack Jachmann, who appeared in Forbes magazine in 2020, and coordinated successful clinical trials at the famous Joselyn Centre (a world leading centre for diabetes care) where, for the first time, real-time changes in glucose concentrations were accurately monitored using a non-invasive nano-electronic patch.
During the 2 day 14 h programme on Monday and Tuesday of this week, undergraduate students from UMFST and other volunteers kindly gave up their precious time to undergo treatment involving modulated electrical impulse-mediated trans-epithelial activation, to assess the capability to improve hyaluronic acid absorption through the epidermal layers of the skin.
Effective delivery of drugs and cosmetics is hampered by the skin’s natural barrier function- and this limits intra-dermal delivery as a therapeutic option. Among other measurements, moisture levels, barrier function and trans-epidermal fluid retention capacity, pigmentation and the local tolerance were examined.
Professor Mark Slevin, scientific director of CCAMF and a close colleague of Jack Jachmann, said ” if the study identifies a novel mechanism through which penetration of active biological medicines can be significantly increased, this opens the door to the possibility of introducing more effective treatments for skin pathologies, including diabetic and complex wounds and ulcers, in addition to supporting skin anti-ageing strategies in the cosmetics and aesthetics industries”. We await the results with anticipation!
Professor Mark Slevin PhD2, FRCPath, FAHA
Scientific Director of CCAMF –
[Centrul Avansat de Cercetări Medicale și Farmaceutice]
University of Medicine, Pharmacy, Science and Technology “George Emil Palade” of Târgu Mureș, Romania
and
Professor of Cell Pathology-
Manchester Metropolitan University